Dr. Pramod Kumar Yadav
Ramalingaswami Fellow
Molecular Enzymology, Biochemistry, H2S Metabolism & Signaling, Structural Biology, Cryo-Electron Microscopy (Single Particle, Helical Reconstruction)
e-mail: pky@nerist.ac.in
Links to Individual Pages/Blogs: https://scholar.google.com/citations?user=LR2Z7cEAAAAJ&hl=en
- Professional Background
- Honors and Awards
- Educational Details
- Administrative Background
- Sponsored Research Projects
- Memberships in Professional bodies
- Teaching Engagements
- Projects and Thesis Supervised/ Currently Supervising
- Ph Ds Supervised
- Special Lectures Delivered
- Publications
- Miscellaneous
| From | To | Designation | Organisation |
|---|---|---|---|
| 12/2020 | Continuing | Ramalingaswami Fellow | NERIST |
| 03/2018 | 10/2020 | Research Lab Specialist Associate | Life Sciences Institute, University of Michigan, USA |
| 09/2016 | 02/2018 | Research Investigator | University of Michigan Medical School, USA |
| 04/2010 | 09/2016 | Research Fellow | University of Michigan Medical School, USA |
| 02/2009 | 03/2010 | Research Associate | TIFR, Mumbai |
| Award | Institute | Year |
|---|---|---|
| Ramalingaswami Re-entry Fellowship | Department of Biotechnology, New Delhi | 2020 |
| Postdoctoral Fellowship | American Heart Association, USA | 2013 |
| Senior Research Fellowship | Council of Scientific and Industrial Research (CSIR), New Delhi | 2008 |
| Degree | Subject | University | Year |
|---|---|---|---|
| Ph.D. | Biotechnology | DDU Gorakhpur University, India | 2009 |
| From | To | Designation | Organisation |
|---|---|---|---|
| Funding Agency | Year | |
|---|---|---|
|
Crosstalk of human hydrogen sulfide producing enzymes and copper relevant in pathophysiology Monetary value sanctioned: Total = 1,13,60,000.00 (INR) |
Department of Biotechnology, New Delhi, India | 2020 -2025 |
|
Regulation of human cystathionine beta-synthase-a multifunctional enzyme Monetary value sanctioned: Total = 1, 02,040.00 (US Dollars) |
American Heart Association, U.S.A. | 2014 - 2015 |
- Biotech Research Society of India, Trivandrum, India (Life-member)
- TIFR Alumni Association, Tata Institute of Fundamental Research, Mumbai, India (Life-member)
- American Heart Association, Dallas, USA (1/2013 to 12/2016)
| Title | Course Code | Module | Semester |
|---|---|---|---|
| I |
| Title of Project | Names of Students |
|---|---|
| Topic | Scholar Name | Status of PHD | Registration Year |
|---|---|---|---|
Participation in short term courses
| Course Name | Sponsored By | Date |
|---|---|---|
| Workshop on “Protein structure prediction and application in agriculture and veterinary” | Bioinformatics Sub-DIC, Department of Molecular Biology & Genetic Engineering, CBSH, G.B. Pant University of Agric. and Technology, Pantnagar, Uttrakhand, India | September 09-11, 2008 |
| Workshop on “Biological sequence analysis and application in crop improvement” | Bioinformatics Sub-DIC, Department of Molecular Biology & Genetic Engineering, CBSH, G.B. Pant University of Agric. and Technology, Pantnagar, Uttrakhand, India | November 16-17, 2007 |
| Workshop on “Creation and Management of Biological databases | Bioinformatics Sub-DIC, Department of Molecular Biology & Genetic Engineering, CBSH, G.B. Pant University of Agric. and Technology, Pantnagar, Uttrakhand, India | February 22-24, 2007 |
| Workshop on “Fundamentals of Protein Docking” | Bioinformatics Sub-DIC, Department of Molecular Biology & Genetic Engineering, CBSH, G.B. Pant University of Agric. And Technology, Pantnagar, Uttaranchal, India | October 18-20, 2006 |
| Title | Place | Date |
|---|---|---|
Some Significant Publications:
|
SI. No. |
Authors |
Title with Volume & Page Nos. |
Journal |
Impact factor |
Citation till date (>1600) |
|
1 |
L E Williamson, T Gilliland, P K Yadav, E Binshtein, R Bombardi, N Kose, R S Nargi, R M Sutton, C L Durie, E Armstrong, R H Carnahan, L M Walker, A S Kim, J Fox, M S Diamond, M D Ohi, W B Klimstra, J E Crowe |
Human antibodies protect against aerosolized Eastern equine encephalitis virus infection. 2020; 183, 1884-1900.e23 (My Contribution: Solved two high resolution CryoEM structure of Virus-human antibody complex) |
Cell |
38.6 |
-- |
|
2 |
S M Fantin , K F Parson, P K Yadav, B Juliano, G C Li, C R Sanders, M D Ohi, B T Ruotolo |
Ion Mobility – Mass Spectrometry Reveals the Role of Peripheral Myelin Protein Dimers in Peripheral Neuropathy. 2021, 118(17), e2015331118
|
Proceedings of the National Academy of Sciences |
9.4 |
-- |
|
3 |
PK Yadav*, V Vitvitsky*, S Carballal*, J Seravalli, R Banerjee *equal contributors |
Thioredoxin regulates human mercaptopyruvate sulfurtransferase at physiologically-relevant concentrations. 2020; 295, 6299-6311 |
Journal of Biological Chemistry |
4.2 |
08 |
|
4 |
P K Yadav, V Vitvitsky, H Kim, A White, U Cho and R Banerjee |
S-3-Carboxypropyl-L-cysteine specifically inhibits cystathionine γ-lyase-dependent hydrogen sulfide synthesis. 2019; 294, 11011-11022 |
Journal of Biological Chemistry |
4.2 |
01 |
|
5 |
AP Landry, S Moon, H Kim, P K Yadav, AGuha, U Cho, R Banerjee |
A Catalytic Trisulfide in Human Sulfide QuinoneOxidoreductase Catalyzes Coenzyme A PersulfideSynthesis and Inhibits Butyrate Oxidation.2019; 26, 1515-1525 |
Cell Chemical Biology |
7.7 |
09 |
|
6 |
|
Structural Organization of the Guinea Pig αA-Crystallin and αA66-80 Peptide Complex. 2019; 25 (Suppl 2): 1318-1319. Paper from Cryo-EM Work |
Microscopy and Microanalysis |
3.4 |
-- |
|
7 |
M Ruetz, G C Campanello, L McDevitt, A L Yokom, P K Yadav, D Watkins, David S. Rosenblatt, M D Ohi, D R Southworthand R Banerjee |
Allosteric regulation of oligomerization by a B12 trafficking G-protein is corrupted in methylmalonic aciduria. 2019; 26: 1–10. Paper from Negative Stain-EM Work |
Cell Chemical Biology |
7.7 |
01 |
|
8 |
V Vitvitsky, JL Miljkovic, T Bostelaar, B Adhikari, P K Yadav, A K Steiger, R Torregrossa, M D Pluth, M Whiteman, R Banerjee, and M R Filipovic |
Cytochrome c Reduction by H2S Potentiates Sulfide Signaling. 2018; 13: 2300-2307. |
ACS Chemical Biology |
4.4 |
27 |
|
9 |
V Vitvitsky, P K Yadav, S An, J Seravalli, U Cho, R Banerjee |
Structural and mechanistic insights into hemoglobin catalyzed hydrogen sulfide oxidation and the fate of polysulfide products. 2017; 292: 5584–5592. |
Journal of Biological Chemistry |
4.2 |
28 |
|
10 |
P K Yadav, M Martinov, V Vitvitsky, J Seravalli, R Wedmann, M R Filipovic, R Banerjee |
Biosynthesis and reactivity of cysteine persulfides in signaling. 2016; 138: 289-299. |
Journal of the American Chemical Society |
14.6 |
138 |
|
11 |
T Bostelaar, V Vitvitsky, J Kumutima, B E Lewis, P K Yadav,T C Brunold, M Filipovic, N Lehnert, T L Stemmler, R Banerjee |
Hydrogen sulfide oxidation by myoglobin. 2016; 138, 8476−8488. |
Journal of the American Chemical Society |
14.6 |
71 |
|
12 |
R Wedmann, C Onderka, S Wei, I A Szijártó, J Miljkovic, A Mitrovic, M Lange, S Savitsky, P K Yadav, R Torregrossa, E G. Harrer, T Harrer I Ishii, M Gollasch,M E Wood, E Galardon, M Xian, MWhiteman, R Banerjee, M R Filipovic |
Improved tag-switch method reveals that thioredoxin controls intracellular levels of protein persulfidation. 2016; 7: 3414–3426. |
Chemical Science |
9.3 |
100 |
|
13 |
S Carballal, E Cuevasanta, P K Yadav, C Gherasim, D P Ballou, B Alvarez, R Banerjee |
Kinetics of Nitrite Reduction and Peroxynitrite Formation by Ferrous Heme in Human Cystathionine β-Synthase. 2016; 291: 8004-8013. |
Journal of Biological Chemistry |
4.2 |
15 |
|
14 |
R Banerjee, T Chiku, O Kabil, M Libiad, N Motl, P K Yadav |
Assay Methods for H2S Biogenesis and Catabolism Enzymes, 2015; 189–200. |
Methods in Enzymology (eds. C Enrique, P Lester) |
Book Chapter |
22 |
|
15 |
T V Mishanina, P K Yadav, D P Ballou, R Banerjee |
Transient kinetic analysis of hydrogen sulfide oxidation catalyzed by human sulfide quinone oxidoreductase. 2015; 290: 25072–25080. |
Journal of Biological Chemistry |
4.2 |
40 |
|
16 |
V Vitvitsky, P K Yadav, A Kurthen, R Banerjee |
Sulfide Oxidation by a Noncanonical Pathway in Red Blood Cells Generates Thiosulfate and Polysulfides. 2015; 290: 8310-8320. |
Journal of Biological Chemistry |
4.2 |
97 |
|
17 |
W Niu, P K Yadav, J Adamec, R Banerjee |
S-Glutathionylation enhances human cystathionine-β- synthase activity under oxidative stress conditions. 2015; 22: 350-361. Selected as cover page article. |
Antioxidant & Redox Signaling |
7.0 |
69 |
|
18 |
M Libiad*, P K Yadav*, V Vitvitsky, M Martinov, R Banerjee *equal contributors in alphabetical order. |
Organization of the human mitochondrial H2S oxidation pathway. 2014; 289: 30901-30910 Highlighted as Paper of the Week |
Journal of Biological Chemistry |
4.2 |
144 |
|
19 |
C Gherasim, P K Yadav, O. Kabil, W. Niu, R Banerjee |
Nitrite reductase activity and inhibition of H2S biogenesis by human cystathionine β-synthase. 2014; 9: e85544. |
PLoS ONE |
2.7 |
36 |
|
20 |
N Motl*, P Yadav*, R Banerjee. *equal contributors in alphabetical order. |
Enzymology of hydrogen sulfide turnover, 2013; 1-35. (ed. H. Kimura). Springer-Verlag Wien |
Hydrogen Sulfide and Its Therapeutic Applications |
Book Chapter |
4 |
|
21 |
P K Yadav, K Yamada, T Chiku, M Koutmos, R Banerjee |
Structure and kinetic analysis of H2S production by human mercaptopyruvate sulfurtransferase. 2013; 288: 20002-20013. |
Journal of Biological Chemistry |
4.2 |
162 |
|
22 |
P K Yadav & R Banerjee |
Detection of reaction intermediates during human cystathionine β-synthase monitored turnover and H2S production. 2012; 287: 43464-43471. |
Journal of Biological Chemistry |
4.2 |
17 |
|
23 |
P K Yadav, P Xie, R Banerjee |
Allosteric communication between the pyridoxal 5′-phosphate (PLP) and heme sites in the H2S generator human cystathionine β-synthase. 2012; 287: 37611–37620. |
Journal of Biological Chemistry |
4.2 |
28 |
|
24 |
P K Yadav, V K Singh, S Yadav, K D S Yadav, D Yadav |
In silico analysis of pectin lyase and pectinase sequences. 2009; 74: 1049-1055. |
Biochemistry (Moscow) |
1.9 |
46 |
|
25 |
S Yadav, P K Yadav, D Yadav, K D S Yadav |
Pectin lyase: a review. 2009; 44:1–10. |
Process Biochemistry |
2.9 |
236 |
|
26 |
V Yadav, P K Yadav, S Yadav, K D S Yadav |
α - L-rhamnosidase: A review. 2010:45: 1226-1235. |
Process Biochemistry |
2.9 |
178 |
|
27 |
S Yadav, P K Yadav, D Yadav, K D S Yadav |
Purification and characterization of an alkaline pectin lyase from Aspergillus flavus. 2008; 43: 547-552. |
Process Biochemistry |
2.9 |
81 |
|
28 |
S Yadav, P K Yadav, D Yadav, K D S Yadav |
Purification and Characterization of pectin lyase produced by Aspergillus terricola and its application in retting of natural fibers.. 2009; 159:270–283. |
Applied Biochemistry and Biotechnology |
2.2 |
44 |
|
29 |
S Yadav, P K Yadav, D Yadav, K D S Yadav |
Purification and characterization of pectin lyase secreted by Penicillium citrinum. 2009; 74: 800-806. |
Biochemistry (Moscow) |
1.9 |
14 |
|
30 |
S Yadav, P K Yadav, D Yadav, K D S Yadav |
Purification and characterization of an acidic pectin lyase produced by Aspergillus ficuum strain MTCC 7591 suitable for clarification of fruit juices. 2008; 58:61-65. |
Annals of Microbiology |
1.40 |
20 |
|
31 |
S Yadav, P K Yadav, D Yadav, K D S Yadav |
Production of pectin lyases from few fungal strains. 2007; 66:601-604. |
Journal of Scientific & Industrial Research |
0.7 |
7 |
|
32 |
P K Yadav, V Kashyap and D Yadav |
Induction and proliferation of callus derived from different explants of Flacourtia Jangomas (Lour.) Raeusch, a woody medicinal plant..2008; 2: 21-24. |
The Icfai Journal of Life Science |
None |
None |
|
33 |
P K Yadav, V Kashyap and D Yadav |
Genomic DNA extraction methods from leaves of Flacourtia jangomas (Lour.) Raeusch, a woody medicinal plant. 2007; 3:78-83. |
The Icfai Journal of Biotechnology |
None |
None |
|
34 |
D Yadav, S Yadav, R Dwivedi, G Anand and P K Yadav |
Potential of microbial enzymes in retting of natural fibers: A review. 2016; 3:89-99. |
Current Biochemical Engineering |
None |
7 |
Paper presented at international conferences
ABSTRACTS/PAPERS PUBLISHED IN CONFERENCES/SYMPOSIUM: (§Poster presented)
- 1. P K Yadav, M Su, S Jeyarajan, F J GiblinStructural Organization of the Guinea Pig αA-Crystallin and αA66-80 Peptide Complex. M&M 2019 Microscopy & MicroAnalysis Meeting. Oregon Convention Center, Portland, U.S.A., August 04-08, 2019.
- 2. P K Yadav §, M Martinov, V Vitvitsky, J Seravalli, R Wedmann, M R Filipovic, R Banerjee. Physiological significance of persulfide generation by the transsulfuration pathway Experimental Biology Meeting. McCormick Place Convention Center, Chicago, U.S.A., April 22–26, 2017.
- 3. P K Yadav §, M Martinov, V Vitvitsky, J Seravalli, R Wedmann, M R Filipovic, R Banerjee Physiological significance of persulfide generation by cystathionine γ-lyase and heme-regulated cystathionine β-synthase. Gordon Research Conference on Metals in Medicine. Proctor Academy Andover, NH, U.S.A., June 26 - July 1, 2016.
- 4. V Vitvitsky, P K Yadav, A. Kurthen, J Seravalli T Bostelaar, R Banerjee. Oxidation of sulfide in red blood cells by methemoglobin. Gordon Research Conference on Metals in Medicine. Proctor Academy Andover, NH, U.S.A., June 26 - July 1, 2016
- 5. T Bostelaar, V Vitvitsky, J Kumutima, B E Lewis, P K Yadav,T C Brunold, M Filipovic, N Lehnert, T L Stemmler, R Banerjee. Hydrogen sulfide oxidation by myoglobin Gordon Research Conference on Metals in Medicine. Proctor Academy Andover, NH, U.S.A., June 26 - July 1, 2016
- 6. P K Yadav § and R Banerjee. Kinetics Analysis of H2S Oxidation by Human Sulfide Quinone Oxidoreductase. 8th International Conference on the Biology, Chemistry and Therapeutic Application of Nitric Oxide & 6th International Meeting on the Role of Nitrite and Nitrate in Physiology, Pathophysiology, and Therapeutics. Cleveland, Ohio, U.S.A., June 16-20, 2014.
- 7. V Vitvitsky, P K Yadav, A Kurthen, R Banerjee. Hydrogen Sulfide Metabolism in Red Blood Cells. 8th International Conference on the Biology, Chemistry and Therapeutic Application of Nitric Oxide & 6th International Meeting on the Role of Nitrite and Nitrate in Physiology, Pathophysiology, and Therapeutics. Cleveland, Ohio, U.S.A., June 16-20, 2014.
- 8. P K Yadav §, T Chiku, R Banerjee. Evaluation of the role of human 3-mercaptopyruvate sulfurtransferase in H2S biogenesis. Second International Conference on H2S Biology and Medicine. Atlanta, Georgia, U.S.A. September.20-22, 2012.
- 9. P K Yadav § and S Mazumdar. Ceruloplasmin from serum of Capra aegagrus hircus. Symposium on Advanced Biological Inorganic Chemistry. Tata Institute of Fundamental Research, Mumbai, India, November 2-4, 2009.
- 10. P K Yadav, S Yadav, D Yadav, K D S Yadav. Pectin lyase: A potential enzyme for fruit juice industries. National Conference on Engineering for Food and Bio-Processing. College of Technology, G.B. Pant University of Agric. and Technology, Pantnagar, Uttrakhand, India. February 2009.
- 11. P K Yadav §, S Yadav, VK Singh, D Yadav, K D S Yadav. In-Silico analysis of pectin lyases and constructing phylogenetic tree based on protein sequences. 3rd International Congress on Bioprocessin Food Industries & 5th Convention of the Biotech Research Society of India. Osmania University, Hyderabad, India. November 2008.
- 12. S Yadav, P K Yadav §, K D S Yadav. Production of pectin lyase by Penicillium sp. induced by sugarcane juice. 3rd BRSI convention and International conference on exploring horizon in Biotechnology. Sardar Patel University, Vallabh Vidyanagar, Gujarat, India. November 2006.
- 13. S Yadav, P K Yadav, D Yadav, K D S Yadav. Studies on pectin lyase produced from indigenously isolated fungal strains. Second convention BRSI. Anna University, Chennai, India. November 2005.
- 14. P K Yadav, V Kashyap, D Yadav. Standardization for callus induction using different explants ofFlacourtia jangomas(Lour.) Raeusch, a woody medicinal plant. Second convention BRSI. Anna University, Chennai, India. November 2005.
- 15. V Kashyap, P K Yadav, V K Morya, S K Mishra, D Yadav. Plant tissue culture of Flacourtia jangomas(Lour.) Raeusch, an endangered plant”. National sensitization programme on biotechnology, organized by small Industries service Institute, Ministry of small scale industries Govt. of India, Gorakhpur, India. March 2005.